The universe works perfectly, whether you understand it or not.1
This is a profoundly mystical statement by the great Frank Zappa, which can be interpreted in two ways.
Is the creative genius inferring that the attempts to explain the universe by rational thinking philosophers and scientists have thus far have feeble? Or is Zappa negating the importance of science as a means of providing purpose in life, although acknowledging its strength in providing a description of the physical world.
I don’t think he could have intended to say that science is useless and all work by engineers and scientists, as he himself was one of the pioneers of composing electronic music using the Synclavier. Zappa can thus by no means be called a sceptic regarding science and its attempt to provide a model of the world.
His statement has to be interpreted as a existential claim about the value of our rational attempts to explain how and why the universe works the way it does. The fact that we now have some clue on the mechanics of the universe does not imply that we have a better culture than, for example, traditional cultures around the globe, who base their explanations on mythology and religion.
The way I see this statement is as an implicit acknowledgement that science and technology should not have primacy over more intuitive modes of explanation. Religion and mythology are not archaic forms of science, they are simply complementary systems.